Gaofeng Wang, Ph.D.
- Associate Professor, Dr. John T. Macdonald Foundation Department of Human Genetics
- Associate Professor, Ophthalmology
- Director, Division for Functional Genomics in the Center for Molecular Genetics, John P. Hussman Institute for Human Genomics
- Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine.
- S-nitrosylation of ApoE in Alzheimer's disease.
- Localization of age-related macular degeneration-associated ARMS2 in cytosol, not mitochondria.
- Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein.
- Nitric oxide regulates endocytosis by S-nitrosylation of dynamin.
Division Director in the Division of Functional Genomics in the Center for Human Molecular Genetics at the John P. Hussman Institute for Human Genomics. His lab studies the functional genomics of hereditary diseases and redox in epigenetic regulation. Wang's work focuses on the regulation of epigenome by vitamin C and the chromosome 10q26 locus in age-related macular degeneration. He is also an Associate Professor in the Dr. John T. Macdonald Foundation Department of Human Genetics.