Dale Hedges, Ph.D.
- Voluntary Assistant Professor, Dr. John T. Macdonald Foundation Department of Human Genetics
- Exome sequencing of a multigenerational human pedigree.
- Inviting instability: Transposable elements, double-strand breaks, and the maintenance of genome integrity.
- Modeling the amplification dynamics of human alu retrotransposons.
- Differential Alu mobilization and polymorphism among the human and chimpanzee lineages.
- Age at onset in two common neurodegenerative diseases is genetically controlled.
- List of Publications
Dale J. Hedges, Ph.D., is the Co-Director of Research Informatics and Associate Director of the Center for Genome Technology at the John P. Hussman Institute for Human Genomics. His research interests span several areas, including mobile genetic elements and their relationship to human disease. He laboratory is engaged in basic research surrounding host regulation of retrotransposon activity and the associated impact on local chromatin structure. Dr. Hedges is actively involved in projects that seek to discover of genetic risk factors for Non-Syndromic Cleft Lip and Palate, Neural Tube Defects, and Autism. He employs a mixture of laboratory and computational methods, and members of his laboratory have an opportunity to participate in both molecular and bioinformatics projects.