Eden R. Martin, Ph.D.
- Director, The Center for Genetic Epidemiology and Statistical Genetics, John P. Hussman Institute for Human Genomics
- Professor, Department of Public Health Sciences
- Professor, Dr. John T. Macdonald Foundation Department of Human Genetics
Dr. Martin's research interests include mapping genes in complex diseases (Alzheimers, Parkinsons, autism), statistical methods, DNA sequence data, genetics of Latin American populations.
- A de Novo 1.5 Mb microdeletion on chromosome 14q23.2-23.3 in a patient with autism and spherocytosis.
- Association and gene-gene interaction of SLC6A4 and ITGB3 in autism.
- Common genetic variants on 5p14.1 associate with autism spectrum disorders.
- Dissecting the locus heterogeneity of autism: significant linkage to chromosome 12q14.
- Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism.
- List of Publications
Eden R. Martin, Ph.D., is Director of the Center for Genetic Epidemiology and Statistical Genetics at The John P. Hussman Institute for Human Genomics. She is a statistical geneticist whose interest is in mapping genes for complex diseases like Alzheimer disease, Parkinson disease, and autism. Specifically, her research has focused on developing extensions of a transmission/disequilibrium test (TDT) for linkage and association studies in nuclear families, such as the Pedigree Disequilibrium Test (PDT) for analysis of linkage disequilibrium in general pedigrees, and the APL test for haplotype analysis. She has also developed a suite of analysis programs for the X chromosome and developed methods for testing gene-gene interaction. She is a professor in the Dr. John T. Macdonald Foundation of Human Genetics.