Ramiro E. Verdun, PhD
- Associate Professor
2008 Postdoctoral Training
University of San Martin
- Cyclin-Dependent Kinases Regulate Ig Class Switching by Controlling Access of AID to the Switch Region.
- A novel mouse model for the hyper-IgM syndrome: a spontaneous activation-induced cytidine deaminase mutation leading to complete loss of Ig class switching and reduced somatic hypermutation.
- Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination.
- Alternative end-joining and classical nonhomologous end-joining pathways repair different types of double-strand breaks during class-switch recombination.