UHealth - University of Miami Health System

Mary Bartlett Bunge, Ph.D.

General Information

Mary  Bartlett Bunge, Ph.D.

Contact

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Languages

  • English

Roles

  • Christine E Lynn Distingished Professor of Neuroscience
  • Professor of Cell Biology

CV

Research Interests

Publications

  • Pearse DD, Pereira FC, Marcillo AE, Bates ML, Berrocal YA, Filbin MT, Bunge MB (2004) cAMP and Schwann cells promote axonal growth and functional recovery after SCI. Nat Med 10:610-616.
  • Kanno H, Pressman Y, Moody A, Berg R, Muir EM, Rogers JH, Ozawa H, Itoi E, Pearse DD, Bunge MB (2014) Combination of engineered Schwann cell grafts to secrete neurotrophin and chondroitinase promotes axonal regeneration and locomotion after spinal cord injury. J Neurosci. 34:1838-1855.
  • Ruschel J, Hellal F, Flynn KC, Dupraz S, Elliot D, Tedeschi A, Bates M, Sliwinski C, Brook G, Dobrint K, Peitz M, Brustle O, Norenberg M, Blesch A, Wiedner N, Bunge MB, Bixby JL, Bradke F.(2015)Systemic administration of epothilone B promotes axon regeneration and functional recovery after Spinal Cord Injury. Science 348:347-52.
  • Golden KL, Pearse DD, Blits B, Garg M, Oudega M, Wood PM, Bunge MB (2007) Transduced Schwann cells promote axon growth and myelination after spinal cord injury. Exp Neurol. 207:203-217.

Biography

Mary Bartlett Bunge, Ph.D., is Professor of Cell Biology and Neurological Surgery, and the Christine E. Lynn Distinguished Professor of Neuroscience at the University of Miami Leonard M. Miller School of Medicine, working in The Miami Project to Cure Paralysis. Pursuing an overall goal of promoting nervous system repair, Dr. Bunge was a pioneer in elucidating the structure and function of cells that form myelin and, more recently, in developing a new spinal cord injury model and novel combination strategies to improve repair of the injured spinal cord. Her laboratory currently conducts preclinical studies aimed at developing neuroprotective and neuroregenerative therapies for spinal cord injuries. These therapies include the transplantation of genetically modified cells to facilitate regeneration in damaged spinal cords. Her work on the contribution of transplanted Schwann cells to spinal cord repair formed part of the basis for gaining approval from the FDA in 2012 for a clinical trial testing these cells in spinal cord injured persons, now underway in the Miami Project.  She has served on NIH study sections and the National Advisory NINDS council. From 1996-1997 she served as Interim Scientific Director of the Miami Project to Cure Paralysis. She has received the Wakeman Award (1996) for her seminal contributions to the field of spinal cord injury repair, the Christopher Reeve Research Medal for Spinal Cord Repair (2001) and the Javits Neuroscience Investigator Award (1998-2005), and was the first recipient of the Mika Salpeter Women in Neuroscience Lifetime Achievement Award (2000). She has also received the Lois Pope LIFE International Research Award (2005) and was inducted into Iron Arrow in 2005, the highest honor at the University of Miami.  In 2012, Dr. Bunge was awarded the Distinguished Faculty Scholar Award (UM); in 2013, elected to the National Academy of Science Institute of Medicine; and, in 2014, was named a Health Care Hero by the Greater Miami Chamber of Commerce. She has received an honorary degree, Doctor of Humane Science, from her alma mater, Simmons College (2006).