Sanjoy K. Bhattacharya, Ph.D.
- Professor of Ophthalmology
Neurodegenerative Disease and Vision
The Bhattacharya laboratory uses a multidisciplinary approach which includes mass spectrometric proteomic and lipidomic approaches to study neurodegenerative diseases. The major focus is a group of progressive irreversible blinding diseases collectively called glaucoma and also a group of demyelinating diseases termed multiple sclerosis that frequently is associated with visual impairment preceding neurological deficits. The lab also has an interest in basic visual processes.
Major focus of the laboratory is ocular neurodegenerative diseases collectively called glaucoma. Our proteomic mass spectrometric analysis differentially identified cochlin and peptidyl arginine deiminase2 associated with diseased human trabecular meshwork and optic nerve tissue respectively. Current projects involve understanding the role that these proteins play in glaucoma pathology.