UHealth - University of Miami Health System

Sandra Merscher, Ph.D.

General Information

Sandra  Merscher, Ph.D.

Contact

  • .(JavaScript must be enabled to view this email address)

Languages

  • English
  • English, German, French

Roles

  • Director of Animal Core
  • Research Associate Professor

CV

Research Interests

Using a basic science and translational research approach, my laboratory is focused on elucidating and understanding the molecular mechanisms that contribute to the development of proteinuria in kidney disease with a focus on focal segmental glomerulorsclerosis (FSGS) and diabetic kidney disease (DKD).

Kidney disease
Mouse models
Podocyte injury
Diabetic kidney disease
Focal segmental glomerulosclerosis
Cell signaling
Cholesterol
Lipids
Sphingolipids
TNF alpha
ABCA1
SMPDL3b.

Awards

Scientific Award Committee
Stanley J. Glaser Foundation Biomedical Research Award

Education

1999 Ph.D.
University of Saarland

Publications

Biography

Dr. Merscher obtained her Ph.D. degree in Human Genetics from the University of Saarland, Saarbrucken, Germany. For her postdoctoral fellowship, she joined Dr. Raju Kucherlapati’s Laboratory in the Department of Molecular Genetics at the Albert Einstein College of Medicine, Bronx, NY and at Brigham and Women’s Hospital, Harvard Medical School, Boston, MA where she worked on the generation and phenotypical analysis of mouse models for Velo-Cardio-Facial Syndrome. Since her postdoctoral fellowship, she has worked as Research Assistant Professor with several investigators from Mount Sinai School of Medicine, New York, NY and the University of Miami, Miller School of Medicine, Miami, FL. specializing in the generation of mouse models for proteinuric kidney diseases. Her research focuses on elucidating and understanding the molecular mechanisms that contribute to the development of proteinuria with a special emphasis on focal segmental glomerulorsclerosis (FSGS) and diabetic kidney disease (DKD).